|Sitemap | Contact|
The drug addiction Newsletter is published periodically, and provides up-to-date information concerning advancements in the treatment of drug addiction, as well as drug addiction trends.
Facts About the Most Used and Abused Drugs from Alcohol to Ecstasy:
Experimental Smoking Vaccine Shows Promise
Clinical trials indicate that an experimental vaccine is showing early signs of effectiveness in helping people stop smoking, Peer View Press reported Sept. 7.
Scientists said NicVax, a nicotine conjugated vaccine, appears to effectively block inhaled smoke from crossing the blood-brain barrier.
Nabi Biopharmaceuticals in Rockville, Md., developed the vaccine, while the trials were conducted by Edwin Wagena, M.D., a health scientist at Maastricht University in the Netherlands.
For the study, 18 healthy smokers and six non-smokers were injected with a 100mcg dose of the vaccine on days 0, 14, 28, and again at six months. A group of three smokers and three nonsmokers received a placebo.
Researchers measured the concentration of antibodies the body produced in response to the vaccine, as well as nicotine concentrations in the blood and the nicotine marker cotinine in the urine. Overall, the researchers found that the levels of nicotine in the blood stream following the injections increased eight-fold by the end of six months, while the amount crossing the blood-brain barrier decreased by 75 percent.
According to Wagena, the vaccine caused the body to produce immunoglobulin G (IgG) antibodies that bind to the inhaled nicotine. This resulted in an antigen/antibody complex that was too large to cross the blood-brain barrier.
A key finding of the study, said Wagena, is that smokers taking part in the study didn't increase their smoking to compensate for no longer getting a big dose of nicotine from each cigarette.
Wagena said additional studies are being conducted in the United States to find different dosing schedules for the drug. The proper dosing schedule will assist clinicians in determining when to initiate and end therapy.
What is Rapid Detox?
Also referred to as 'ultra rapid opiate detox,' it is a rapid detoxification procedure for opiate based substances and addictions such as heroin, vicodin, methadone, or any prescribed narcotic pain killers.
· alcoholism · stimulants · heroin addiction · methamphetamines
cocaine addiction · marijuana addiction · prescription drugs · hallucinogens
drunk driving · dual diagnosis · oxycontin ® · drugs and denial · ecstasy
truths about cocaine · opioids · what is lsd · drugs at work
what is alcoholism · rehab programs · cns depressants · site map
|Home | Get Help Now! | About Rehabs | About Us | Resources|
|Nothing contained on the Drug Addiction Treatment Center web site is intended to be used for medical diagnosis or treatment or as a substitute for consultation with a qualified health care professional. Drug Addiction Treatment Center contains advertisements and links to third party websites. Drug Addiction Treatment Center does not make any representation, warranty, or endorsement of any product or service or the content or accuracy of any materials contained in, or linked to, any advertisement or link on the Site|